New Edges of RNA Adenosine Methylation Modifications | Zendy

Ye Wang | Zendy; Guifang Jia | Zendy

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New Edges of RNA Adenosine Methylation Modifications

Author(s) -

Ye Wang,

Guifang Jia

Publication year - 2016

Publication title -

genomics proteomics and bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.114

H-Index - 49

eISSN - 2210-3244

pISSN - 1672-0229

DOI - 10.1016/j.gpb.2016.05.003

Subject(s) - adenosine , methylation , rna methylation , rna , biology , computational biology , genetics , biochemistry , methyltransferase , dna , gene

Recently an article published in Molecular Cell reveals the mechanism of a nuclear N6-methyladenosine (m6A) reader, the YTH domain-containing protein 1 (YTHDC1), in regulating pre-mRNA splicing [1]. Meanwhile, two additional articles published in Nature and Nature Chemical Biology report the first transcriptome-wide maps of N1-methyladenosine (m1A) at high resolution, suggesting a functional role for m1A in translation regulation [2], [3].

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