Methotrexate-induced hemothorax in a woman with low-risk metastatic gestational trophoblastic disease
Author(s) -
Yuji Ohki,
Hisako Yamada,
Yusuke Taira,
Wataru Kudaka,
Yoichi Aoki
Publication year - 2019
Publication title -
gynecologic oncology reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.557
H-Index - 15
ISSN - 2352-5789
DOI - 10.1016/j.gore.2019.100517
Subject(s) - medicine , methotrexate , gestational trophoblastic disease , chemotherapy , vascularity , chorioepithelioma , surgery , hemothorax , radiology , pregnancy , choriocarcinoma , gestation , pneumothorax , biology , genetics
Highlights • Patients with invasive mole have a risk of bleeding to fragility and vascularity of the tumor.• Some patients may experience life-threatening bleeding.• Chemotherapy of patients with invasive/metastatic mole may induce bleeding.• In our patient with pulmonary metastatic mole, massive hemorrhage occurred 2 h after the first dose of MTX.• Our patient was successfully treated with partial resection of the bleeding tumor and additional 2 cycles of MTX.
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