Open AccessTranslocation of proteins across archaeal cytoplasmic membranes
Author(s) -
Pohlschröder Mechthild,
Dilks Kieran,
Hand Nicholas J,
Wesley Rose R
Publication year - 2004
Publication title -
fems microbiology reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.91
H-Index - 212
eISSN - 1574-6976
pISSN - 0168-6445
DOI - 10.1016/j.femsre.2003.07.004
Subject(s) - archaea , biology , cytoplasm , transport protein , bacteria , membrane transport , chromosomal translocation , membrane protein , membrane , microbiology and biotechnology , biochemistry , genetics , gene
All cells need to transport proteins across hydrophobic membranes. Several mechanisms have evolved to facilitate this transport, including: (i) the universally‐conserved Sec system, which transports proteins in an unfolded conformation and is thought to be the major translocation pathway in most organisms and (ii) the Tat system, which transports proteins that have already obtained some degree of tertiary structure. Here, we present the current understanding of these processes in the domain Archaea, and how they compare to the corresponding pathways in bacteria and eukaryotes.