Open AccessCoordination of DNA replication and cell division in Cyanobacteria Microcystis aeruginosa
Author(s) -
Yoshida Takashi,
Maki Misae,
Okamoto Hideaki,
Hiroishi Shingo
Publication year - 2005
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1016/j.femsle.2005.07.041
Subject(s) - ftsz , dna replication , cell division , control of chromosome duplication , biology , dna , microbiology and biotechnology , transcription (linguistics) , origin recognition complex , cell cycle , eukaryotic dna replication , pre replication complex , dna synthesis , cell , genetics , linguistics , philosophy
Little is known about the cyanobacterial cell cycle. When either nalidixic acid or hydroxyurea was added to a synchronized culture of Microcystis aeruginosa to block DNA replication, cell division did not occur. Furthermore, transcription of the essential cell division gene, ftsZ was repressed. After DNA replication, ftsZ transcription, as well as cell division, was not affected by hydroxyl urea, suggesting that the DNA replication and cell division of M. aeruginosa are coordinated and that this coordination is partly controlled by ftsZ transcription depending on DNA replication.