Open AccessMycoplasma bovis shares insertion sequences with Mycoplasma agalactiae and Mycoplasma mycoides subsp. mycoides SC: Evolutionary and developmental aspects
Author(s) -
Thomas Anne,
Linden Annick,
Mainil Jacques,
Bischof Daniela F.,
Frey Joachim,
Vilei Edy M.
Publication year - 2005
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1016/j.femsle.2005.03.013
Subject(s) - mycoplasma mycoides , biology , microbiology and biotechnology , pathogen , mycoplasma , insertion sequence , genome , genetics , gene , transposable element
Three new insertion elements, IS Mbov1 , IS Mbov2 and IS Mbov3 , which are closely related to IS Mag1 ( Mycoplasma agalactiae ), IS Mmy1 and IS 1634 (both Mycoplasma mycoides subsp. mycoides SC), respectively, have been discovered in Mycoplasma bovis , an important pathogen of cattle. Southern blotting showed that the genome of M. bovis harbours 6–12 copies of IS Mbov1 , 11–15 copies of IS Mbov2 and 4–10 copies of IS Mbov3 , depending on the strain. A fourth insertion element, the IS 30 ‐like element, is present in 4–8 copies. This high number of IS elements in M. bovis , which represent a substantial part of its genome, and their relatedness with IS elements of both M. agalactiae and M. mycoides subsp. mycoides SC suggest the occurrence of two evolutionary events: (i) a divergent evolution into M. agalactiae and M. bovis upon infection of different hosts; (ii) a horizontal transfer of IS elements during co‐infection with M. mycoides subsp. mycoides SC and M. bovis of a same bovine host.