Open AccessGlutamic protease distribution is limited to filamentous fungi
Author(s) -
Sims Andrew H.,
DunnColeman Nigel S.,
Robson Geoffrey D.,
Oliver Stephen G.
Publication year - 2004
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1016/j.femsle.2004.08.023
Subject(s) - proteases , biology , phanerochaete , protease , genome , basidiomycota , glutamic acid , microbiology and biotechnology , genetics , biochemistry , botany , enzyme , gene , amino acid
Glutamic proteases are a distinct, and recently re‐classified, group of peptidases that are thought to be found only in fungi. We have identified and analysed the distribution of over 20 putative glutamic proteases from all fungal species whose genomes have been sequenced so far. Although absent from the Saccharomycetales class, glutamic proteases appear to be present in all other ascomycetes species examined. A large number of coding regions for glutamic proteases were also found clustered together in the Phanerochaete chrysosporium genome, despite apparently being absent from three other species of Basidiomycota.