Open AccessGeographical distribution of genetic polymorphism of the pathogen Histoplasma capsulatum isolated from infected bats, captured in a central zone of Mexico
Author(s) -
Taylor Maria Lucia,
ChávezTapia Catalina B.,
RojasMartínez Alberto,
Rocio ReyesMontes Maria,
Valle Mirian Bobadilla,
Zúñiga Gerardo
Publication year - 2005
Publication title -
fems immunology & medical microbiology
Language(s) - English
Resource type - Journals
eISSN - 1574-695X
pISSN - 0928-8244
DOI - 10.1016/j.femsim.2005.05.019
Subject(s) - biology , histoplasma capsulatum , genetic diversity , genotype , population , histoplasma , pathogen , strain (injury) , polymerase chain reaction , genetic variability , virology , microbiology and biotechnology , genetics , gene , histoplasmosis , immunology , demography , anatomy , sociology
Fourteen Histoplasma capsulatum isolates recovered from infected bats captured in Mexican caves and two human H. capsulatum reference strains were analyzed using random amplification of polymorphic DNA PCR‐based and partial DNA sequences of four genes. Cluster analysis of random amplification of polymorphic DNA‐patterns revealed differences for two H. capsulatum isolates of one migratory bat Tadarida brasiliensis . Three groups were identified by distance and maximum‐parsimony analyses of arf , H‐anti , ole , and tub1 H. capsulatum genes. Group I included most isolates from infected bats and one clinical strain from central Mexico; group II included the two isolates from T. brasiliensis ; the human G‐217B reference strain from USA formed an independent group III. Isolates from group II showed diversity in relation to groups I and III, suggesting a different H. capsulatum population.