Methylome-wide association study provides evidence of particulate matter air pollution-associated DNA methylation
Author(s) -
Rahul Gondalia,
Antoine Baldassari,
Katelyn M. Holliday,
Anne E. Justice,
Raúl Méndez-Giráldez,
James D. Stewart,
Duanping Liao,
Jeff D. Yanosky,
Kasey Brennan,
Stephanie M. Engel,
Kristina M. Jordahl,
Elizabeth M. Kennedy,
Cavin WardCaviness,
Kathrin Wolf,
Mélanie Waldenberger,
Josef Cyrys,
Annette Peters,
Parveen Bhatti,
Steve Horvath,
Themistocles L. Assimes,
James S. Pankow,
Ellen W. Demerath,
Weihua Guan,
Myriam Fornage,
Jan Bressler,
Kari E. North,
Karen N. Conneely,
Yun Li,
Lifang Hou,
Andrea Baccarelli,
Eric A. Whitsel
Publication year - 2019
Publication title -
environment international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.582
H-Index - 191
eISSN - 1873-6750
pISSN - 0160-4120
DOI - 10.1016/j.envint.2019.03.071
Subject(s) - dnam , particulates , dna methylation , air pollution , methylation , environmental chemistry , environmental science , biology , dna , chemistry , ecology , genetics , gene , gene expression
Ambient PM concentrations were associated with DNAm at genomic regions potentially related to poor health among racially, ethnically and environmentally diverse populations of U.S. women and men. Further investigation is warranted to uncover mechanisms through which PM-induced epigenomic changes may cause disease.
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