Signal Transduction Pathways as Concurrent Reactive Systems: A Modeling and Simulation Approach Using LSCs and the Play-Engine | Zendy

Claudia Täubner | Zendy; Silke Eckstein | Zendy

Open Access

Signal Transduction Pathways as Concurrent Reactive Systems: A Modeling and Simulation Approach Using LSCs and the Play-Engine

Author(s) -

Claudia Täubner,

Silke Eckstein

Publication year - 2008

Publication title -

electronic notes in theoretical computer science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.242

H-Index - 60

ISSN - 1571-0661

DOI - 10.1016/j.entcs.2007.12.011

Subject(s) - signal transduction , transduction (biophysics) , signal (programming language) , computer science , microbiology and biotechnology , biology , programming language , biophysics

ignal transduction pathways describe how cells respond to extracellular signals which are received by receptors at the cell membrane and usually transferred into the nucleus. In this paper we present our approach to model these signal transduction pathways as concurrent reactive systems by means of Life Sequence Charts and to simulate them using the Play-Engine tool. This aspect is part of a bigger approach, where we provide an extendable system to generate models of signal transduction pathways in different modeling languages and to simulate these models with the corresponding simulation tools

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