Open AccessModeling of ACTN4-Based Podocytopathy Using Drosophila Nephrocytes
Author(s) -
Johanna Odenthal,
Sebastian Dittrich,
Vivian Ludwig,
Tim Merz,
Katrin Reitmeier,
Björn Reusch,
Martin Höhne,
Zülfü C. Cosgun,
Maximilian Hohenadel,
Jovana Putnik,
Heike Göbel,
Markus M. Rinschen,
Janine Altmüller,
Sybille Koehler,
Bernhard Schermer,
Thomas Benzing,
Bodo B. Beck,
Paul Brinkkötter,
Sandra Habbig,
Malte P. Bartram
Publication year - 2022
Publication title -
kidney international reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.225
H-Index - 22
ISSN - 2468-0249
DOI - 10.1016/j.ekir.2022.10.024
Subject(s) - medicine , drosophila (subgenus) , computational biology , mathematics , genetics , biology , gene
Genetic disorders are among the most prevalent causes leading to progressive glomerular disease and, ultimately, end-stage renal disease (ESRD) in children and adolescents. Identification of underlying genetic causes is indispensable for targeted treatment strategies and counseling of affected patients and their families.
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