Open AccessISN Forefronts Symposium 2015: The Diverse Function of Macrophages in Renal Disease
Author(s) -
Fiona Duthie,
Eoin O’Sullivan,
Jeremy Hughes
Publication year - 2016
Publication title -
kidney international reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.225
H-Index - 22
ISSN - 2468-0249
DOI - 10.1016/j.ekir.2016.08.004
Subject(s) - medicine , macrophage , immune system , kidney , kidney disease , immunology , inflammation , nephrology , pathology , biology , in vitro , biochemistry
Experimental and human studies indicate that macrophages play a key role within the diseased kidney and represent a target for novel therapies. This brief review outlines the involvement and nature of macrophages in renal disease and highlights the phenotypic plasticity of these cells and their responsiveness to the renal microenvironment
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