Glutathione preconditioning ameliorates mitochondria dysfunction during warm pulmonary ischemia–reperfusion injury | Zendy

Sebastian-Patrick Sommer | Zendy; Stefanie Sommer | Zendy; Bhanu Sinha | Zendy; Daniel Walter | Zendy; Ivan Aleksić | Zendy; Bernhard Gohrbandt | Zendy; Christoph Otto | Zendy; Rainer Leyh | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Glutathione preconditioning ameliorates mitochondria dysfunction during warm pulmonary ischemia–reperfusion injury

Author(s) -

Sebastian-Patrick Sommer,

Stefanie Sommer,

Bhanu Sinha,

Daniel Walter,

Ivan Aleksić,

Bernhard Gohrbandt,

Christoph Otto,

Rainer Leyh

Publication year - 2011

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1016/j.ejcts.2011.02.081

Subject(s) - glutathione , mitochondrion , pulmonary injury , reperfusion injury , ischemia , pharmacology , medicine , anesthesia , chemistry , biochemistry , lung , enzyme , pulmonary fibrosis

Reduced glutathione (GSH) has been shown to improve pulmonary graft preservation. Mitochondrial dysfunction is regarded to be the motor of ischemia-reperfusion injury (IR) in solid organs. We have shown previously that IR induces pulmonary mitochondrial damage. This study elucidates the impact of GSH preconditioning on the integrity and function of pulmonary mitochondria in the setting of warm pulmonary IR.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research