Even short-time storage in physiological saline solution impairs endothelial vascular function of saphenous vein grafts | Zendy

Manuel Wilbring | Zendy; Sems Malte Tugtekin | Zendy; Birgit Zatschler | Zendy; Anette Ebner | Zendy; Hermann Reichenspurner | Zendy; Klaus Matschke | Zendy; Andreas Deußen | Zendy

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Even short-time storage in physiological saline solution impairs endothelial vascular function of saphenous vein grafts

Author(s) -

Manuel Wilbring,

Sems Malte Tugtekin,

Birgit Zatschler,

Anette Ebner,

Hermann Reichenspurner,

Klaus Matschke,

Andreas Deußen

Publication year - 2011

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1016/j.ejcts.2011.01.024

Subject(s) - saline , vein , tail vein , medicine , surgery , anesthesia , cardiology , biology , microbiology and biotechnology , in vivo

A faultless endothelial layer is decisive for vascular function and therewith graft's patency. Functional impairment of the endothelium increases risk of graft thrombosis, intimal hyperplasia, and consecutive accelerated graft atherosclerosis. Storage solutions for intra-operatively harvested saphenous vein segments (SVS) might have significant impact on endothelial function. We investigated the impact of short-time storage in physiological saline solution (PSS) and a potassium-chloride- and N-acetylhistidine-enriched storage solution on venous endothelial function.

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