Lady Windermere revisited: treatment with thoracoscopic lobectomy/segmentectomy for right middle lobe and lingular bronchiectasis associated with non-tuberculous mycobacterial disease☆
Author(s) -
Jessica A. Yu,
Marvin Pomerantz,
Amy Bishop,
Michael J. Weyant,
John D. Mitchell
Publication year - 2011
Publication title -
european journal of cardio-thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 133
eISSN - 1873-734X
pISSN - 1010-7940
DOI - 10.1016/j.ejcts.2010.12.028
Subject(s) - medicine , bronchiectasis , surgery , lung , pneumonectomy , tuberculosis , retrospective cohort study , thoracotomy , thoracoscopy , incidence (geometry) , pathology , physics , optics
Lady Windermere syndrome is a well-known but poorly understood female predominant phenotype of isolated right middle lobe and lingular bronchiectasis associated with non-tuberculous mycobacterial (NTM) infection. Despite lengthy multidrug antibiotic treatment, the presence of damaged parenchymal tissue leads to symptomatic disease recurrence, often with resistant organisms. The use of surgical resection as an adjunct to medical therapy may alter this cycle, although little is known about the use of thoracoscopic lung resection in this patient population.
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