Intracoronary levosimendan prevents myocardial ischemic damages and activates survival signaling through ATP-sensitive potassium channel and nitric oxide☆☆☆ | Zendy

Philippe Primo Caimmi | Zendy; Claudio Molinari | Zendy; Francesca Uberti | Zendy; Ezio Micalizzi | Zendy; Guido Valente | Zendy; David Mary | Zendy; Giovanni Vacca | Zendy; Elena Grossini | Zendy

Open Access

Intracoronary levosimendan prevents myocardial ischemic damages and activates survival signaling through ATP-sensitive potassium channel and nitric oxide☆☆☆

Author(s) -

Philippe Primo Caimmi,

Claudio Molinari,

Francesca Uberti,

Ezio Micalizzi,

Guido Valente,

David Mary,

Giovanni Vacca,

Elena Grossini

Publication year - 2011

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1016/j.ejcts.2010.11.044

Subject(s) - levosimendan , cardioprotection , nitric oxide , medicine , glibenclamide , ischemia , cardiology , cardiac function curve , reperfusion injury , anesthesia , heart failure , endocrinology , diabetes mellitus

Levosimendan has been reported to exert cardioprotection. In this study, we have examined the cardiac effects of different doses of intracoronary levosimendan on ischemia/reperfusion injuries, and the involvement of K(ATP) channels and nitric oxide (NO).

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