Thymoma: inter-relationships among World Health Organization histology, Masaoka staging and myasthenia gravis and their independent prognostic significance: a single-centre experience | Zendy

Enrico Ruffini | Zendy; Pier Luigi Filosso | Zendy; C Mossetti | Zendy; Maria Cristina Bruna | Zendy; Domenico Novero | Zendy; Patrizia Lista | Zendy; Caterina Casadio | Zendy; A Oliaro | Zendy

Open Access

Thymoma: inter-relationships among World Health Organization histology, Masaoka staging and myasthenia gravis and their independent prognostic significance: a single-centre experience

Author(s) -

Enrico Ruffini,

Pier Luigi Filosso,

C Mossetti,

Maria Cristina Bruna,

Domenico Novero,

Patrizia Lista,

Caterina Casadio,

A Oliaro

Publication year - 2010

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1016/j.ejcts.2010.09.042

Subject(s) - thymoma , medicine , stage (stratigraphy) , odds ratio , myasthenia gravis , histology , confidence interval , univariate analysis , logistic regression , population , multivariate analysis , surgery , paleontology , environmental health , biology

In thymomas, World Health Organization (WHO) histology, Masaoka stage and myasthenia gravis (MG) have long been considered important for patient management and outcome. Their role has been independently investigated in the past. Few studies, however, focussed on the correlations among these variables. The aim of the present study was to retrospectively evaluate, in our patient population of resected thymomas, the inter-relationships among MG, WHO histology and Masaoka stage, and to look at how and to what extent one variable is associated with the other two in terms of clinical presentation and survival.

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