The morphological diversity of small lung adenocarcinoma with mixed subtypes is associated with local invasiveness and prognosis | Zendy

Tomohiro Haruki | Zendy; Kohei Shomori | Zendy; Tatsushi Shiomi | Zendy; Yuji Taniguchi | Zendy; Hiroshige Nakamura | Zendy; Hisao Ito | Zendy

Open Access

The morphological diversity of small lung adenocarcinoma with mixed subtypes is associated with local invasiveness and prognosis

Author(s) -

Tomohiro Haruki,

Kohei Shomori,

Tatsushi Shiomi,

Yuji Taniguchi,

Hiroshige Nakamura,

Hisao Ito

Publication year - 2010

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1016/j.ejcts.2010.07.047

Subject(s) - adenocarcinoma , lung , medicine , pathology , lymphovascular invasion , pathological , lung cancer , stage (stratigraphy) , adenocarcinoma of the lung , metastasis , oncology , cancer , biology , paleontology

Under the current World Health Organization (WHO) classification, 'lung adenocarcinoma with mixed subtypes' is the most frequent type, even in small lung adenocarcinoma, with a diameter of 3 cm or less. For this type of lung adenocarcinoma, it has been reported that the high ratio of the peripheral bronchioloalveolar carcinoma (BAC)/lepidic growth (LG) component was a favorable prognostic factor. On the other hand, the central solid components of lung adenocarcinoma with mixed subtypes have not been focused on in the past. In this study, we took note of the histological features in central solid components of lung adenocarcinoma with mixed subtypes and evaluated whether the morphological diversity of these tumors is associated with local invasiveness and prognostic implication.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research