Open AccessOral sildenafil for persistent pulmonary hypertension early after congenital cardiac surgery in children☆
Author(s) -
Shintaro Nemoto,
Tomoyasu Sasaki,
Hideki Ozawa,
Takahiro Katsumata,
Kanta Kishi,
Kenichi Okumura,
Yasuhiko H. Mori,
Osamu Umegaki
Publication year - 2010
Publication title -
european journal of cardio-thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 133
eISSN - 1873-734X
pISSN - 1010-7940
DOI - 10.1016/j.ejcts.2010.01.045
Subject(s) - sildenafil , medicine , pulmonary hypertension , cardiac surgery , cardiology
Sildenafil is a strong pulmonary vasodilator that increases the intracellular cyclic guanosine monophosphate concentration through inhibition of phosphodiesterase-5. We assessed the benefit of oral sildenafil for persistent pulmonary hypertension early after congenital cardiac surgery in paediatric patients.
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