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Early failure of xenogenous de-cellularised pulmonary valve conduits — a word of caution!☆
Author(s) -
André Rüffer,
Ariawan Purbojo,
Iwona Cicha,
Martin Glöckler,
Sergej Potapov,
Sven Dittrich,
Robert Cesnjevar
Publication year - 2010
Publication title -
european journal of cardio-thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 133
eISSN - 1873-734X
pISSN - 1010-7940
DOI - 10.1016/j.ejcts.2010.01.044
Subject(s) - medicine , calcification , ventricular outflow tract , ventricle , pulmonary valve , stenosis , surgery , pulmonary artery , cardiology
The longevity of valved right ventricle to pulmonary artery (RV-PA) conduits is limited due to calcification and degeneration of non-viable structures. Xenografts are commonly used because of the restricted availability of cryopreserved homografts. Tissue-engineered (de-cellularised) pulmonary valves (TEPVs) were thought to be a valuable alternative to cryopreserved pulmonary homografts due to postoperative seeding with viable autologous vascular endothelial cells.

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