Exercise ventilatory inefficiency and mortality in patients with chronic obstructive pulmonary disease undergoing surgery for non-small-cell lung cancer | Zendy

Roberto Torchio | Zendy; Marco Guglielmo | Zendy; Roberto Giardino | Zendy; Francesco Ardissone | Zendy; Claudio Ciacco | Zendy; Carlo Gulotta | Zendy; Aleksandar Veljković | Zendy; Massimiliano Bugiani | Zendy

Open Access

Exercise ventilatory inefficiency and mortality in patients with chronic obstructive pulmonary disease undergoing surgery for non-small-cell lung cancer

Author(s) -

Roberto Torchio,

Marco Guglielmo,

Roberto Giardino,

Francesco Ardissone,

Claudio Ciacco,

Carlo Gulotta,

Aleksandar Veljković,

Massimiliano Bugiani

Publication year - 2010

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1016/j.ejcts.2010.01.032

Subject(s) - medicine , pneumonectomy , copd , pulmonary function testing , lung cancer , surgery , lung cancer surgery , respiratory failure , cardiology

Surgical resection is the treatment of choice to cure patients with non-small-cell lung cancer (NSCLC); nevertheless, the assessment of the lower limit of surgical tolerance remains difficult. Ventilatory inefficiency (measured as the ventilation to CO(2) production ratio (V'(E)/V'(CO2) slope) is a survival predictor in pulmonary hypertension (PH) and chronic heart failure (CHF) and is considered a marker of PH in chronic obstructive pulmonary disease (COPD). The aim of this study was to investigate the role of V'(E)/V'(CO2) slope as preoperative mortality and morbidity predictor in COPD patients submitted to lung resection for NSCLC and considered operable according to current standards.

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