Functional closure of visceral pleural defects by autologous tissue engineered cell sheets☆
Author(s) -
Masato Kanzaki,
Masayuki Yamato,
Joseph Yang,
Hidekazu Sekine,
Ryo Takagi,
Tamami Isaka,
Teruo Okano,
Takamasa Onuki
Publication year - 2008
Publication title -
european journal of cardio-thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 133
eISSN - 1873-734X
pISSN - 1010-7940
DOI - 10.1016/j.ejcts.2008.05.048
Subject(s) - fibrin glue , medicine , fibroblast , tissue engineering , transplantation , fibrin , surgery , ex vivo , dermal fibroblast , pathology , biomedical engineering , cell culture , in vivo , immunology , biology , genetics , microbiology and biotechnology
The occurrence of intraoperative air leaks is an unavoidable complication during pulmonary surgeries. However, current surgical methods are generally ineffective in closing these visceral pleural defects, resulting in a decreased quality of life for patients. Here, we examined novel tissue engineered cell sheets for the closure of pleural defects in a porcine model.
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