Intraoperative skeletal muscle ischemia contributes to risk of renal dysfunction following thoracoabdominal aortic repair☆☆☆ | Zendy

Charles C. Miller | Zendy; Martin A. Villa | Zendy; Paul Achouh | Zendy; Anthony L. Estrera | Zendy; Ali Azizzadeh | Zendy; Sheila M. Coogan | Zendy; Eyal Porat | Zendy; Hazim J. Safi | Zendy

Open Access

Intraoperative skeletal muscle ischemia contributes to risk of renal dysfunction following thoracoabdominal aortic repair☆☆☆

Author(s) -

Charles C. Miller,

Martin A. Villa,

Paul Achouh,

Anthony L. Estrera,

Ali Azizzadeh,

Sheila M. Coogan,

Eyal Porat,

Hazim J. Safi

Publication year - 2008

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1016/j.ejcts.2008.01.006

Subject(s) - medicine , renal function , dialysis , cardiology , ischemia , critical limb ischemia , renal ischemia , copd , kidney disease , odds ratio , surgery , anesthesia , revascularization , myocardial infarction , reperfusion injury

Renal dysfunction is among the most commonly occurring morbidities following descending thoracic and thoracoabdominal aortic repair. We hypothesized that myoglobin nephrotoxicity might arise from leg ischemia caused by femoral artery cannulation, which is required for distal aortic perfusion. Lacking complete historical laboratory data on myoglobinemia, we studied somatosensory evoked potential (SSEP) changes in the leg (a functional marker of leg ischemia), as a surrogate predictor of acute postoperative renal failure.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research