Does furosemide prevent renal dysfunction in high-risk cardiac surgical patients? Results of a double-blinded prospective randomised trial☆☆☆ | Zendy

Balakrishnan Mahesh | Zendy; Boyd Yim | Zendy; D. Robson | Zendy; Ravi Pillai | Zendy; Chandana Ratnatunga | Zendy; David C. Pigott | Zendy

Open Access

Does furosemide prevent renal dysfunction in high-risk cardiac surgical patients? Results of a double-blinded prospective randomised trial☆☆☆

Author(s) -

Balakrishnan Mahesh,

Boyd Yim,

D. Robson,

Ravi Pillai,

Chandana Ratnatunga,

David C. Pigott

Publication year - 2008

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1016/j.ejcts.2007.12.030

Subject(s) - furosemide , medicine , creatinine , renal function , ejection fraction , cardiopulmonary bypass , placebo , urology , anesthesia , diabetes mellitus , surgery , heart failure , endocrinology , alternative medicine , pathology

Renal dysfunction following cardiac surgery is more apparent in high-risk patients with pre-existing renal dysfunction, diabetes and impaired left-ventricular function, and following complicated procedures involving prolonged cardiopulmonary bypass (CPB). The aim of this prospectively randomised double-blinded placebo-controlled study was to evaluate reno-protective effect of low-dose furosemide infusion in this high-risk group.

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