Preconditioning effects of steroids and hyperoxia on cardiac ischemia–reperfusion injury and vascular reactivity☆ | Zendy

MariLiis Kaljusto | Zendy; KåreOlav Stensløkken | Zendy; Tomohisa Mori | Zendy; Andrey Panchenko | Zendy; Marthe-Lise Frantzen | Zendy; Guro Valen | Zendy; Jarle Vaage | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Preconditioning effects of steroids and hyperoxia on cardiac ischemia–reperfusion injury and vascular reactivity☆

Author(s) -

MariLiis Kaljusto,

KåreOlav Stensløkken,

Tomohisa Mori,

Andrey Panchenko,

Marthe-Lise Frantzen,

Guro Valen,

Jarle Vaage

Publication year - 2008

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1016/j.ejcts.2007.12.017

Subject(s) - medicine , hyperoxia , ischemia , dexamethasone , kinase , protein kinase b , reperfusion injury , cardioprotection , endocrinology , p38 mitogen activated protein kinases , anesthesia , pharmacology , protein kinase a , chemistry , phosphorylation , biochemistry , lung

Corticosteroids and hyperoxia protect the heart against ischemia-reperfusion injury and may attenuate vascular reactivity. We hypothesized that (1) combining these two pretreatments induces an additive cardioprotection, (2) protection depends on activation of survival kinases and/or heat shock proteins, and (3) these interventions would change vascular reactivity into a more relaxed state.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research