Vascular endothelial growth factor increases pulmonary vascular permeability in cystic fibrosis patients undergoing lung transplantation☆☆☆ | Zendy

Katharina Krenn | Zendy; Walter Klepetko | Zendy; Shahrokh Taghavi | Zendy; Patrick Paulus | Zendy; Seyedhossein Aharinejad | Zendy

Open Access

Vascular endothelial growth factor increases pulmonary vascular permeability in cystic fibrosis patients undergoing lung transplantation☆☆☆

Author(s) -

Katharina Krenn,

Walter Klepetko,

Shahrokh Taghavi,

Patrick Paulus,

Seyedhossein Aharinejad

Publication year - 2007

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1016/j.ejcts.2007.04.006

Subject(s) - vascular endothelial growth factor , lung transplantation , lung , transplantation , cd31 , medicine , vascular permeability , angiogenesis , pathology , hypoxia inducible factors , hypoxia (environmental) , biology , chemistry , vegf receptors , biochemistry , gene , organic chemistry , oxygen

Vascular endothelial growth factor (VEGF) is the prime regulator of angiogenesis and vascular permeability and its serum levels increase in cystic fibrosis (CF). The mechanisms of VEGF overproduction and its impact on CF lung pathology and pulmonary vascular permeability during lung transplantation are not fully understood.

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