PDE-5 inhibitor donor intravenous preconditioning is superior to supplementation in standard preservation solution in experimental lung transplantation☆ | Zendy

Nikolaus Pizanis | Zendy; Vitaly Milekhin | Zendy; Konstantinos Tsagakis | Zendy; Ivan Aleksić | Zendy; Markus Kamler | Zendy; Heinz Jakob | Zendy

Open Access

PDE-5 inhibitor donor intravenous preconditioning is superior to supplementation in standard preservation solution in experimental lung transplantation☆

Author(s) -

Nikolaus Pizanis,

Vitaly Milekhin,

Konstantinos Tsagakis,

Ivan Aleksić,

Markus Kamler,

Heinz Jakob

Publication year - 2007

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1016/j.ejcts.2007.03.044

Subject(s) - sildenafil , medicine , lung transplantation , lung , transplantation , anesthesia , urology , vascular resistance , hemodynamics , surgery

Improvement of preservation is still a major research objective in lung transplantation. The effects of phosphodiesterase-5 (PDE-5) inhibitors during procurement are still not clear. It was the aim of this study to investigate the effect of sildenafil on post-transplanted lung function in a porcine model using different application procedures.

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