Human gastroepiploic artery has greater chymase activity than the internal thoracic artery | Zendy

Yoshiharu Soga | Zendy; Shinji Takai | Zendy; Hitoshi Okabayashi | Zendy; Atsushi Nagasawa | Zendy; Tadaaki Yokota | Zendy; Kazunobu Nishimura | Zendy; Mizuo Miyazaki | Zendy; Masashi Komeda | Zendy

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Human gastroepiploic artery has greater chymase activity than the internal thoracic artery

Author(s) -

Yoshiharu Soga,

Shinji Takai,

Hitoshi Okabayashi,

Atsushi Nagasawa,

Tadaaki Yokota,

Kazunobu Nishimura,

Mizuo Miyazaki,

Masashi Komeda

Publication year - 2006

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1016/j.ejcts.2006.09.030

Subject(s) - right gastroepiploic artery , internal thoracic artery , gastroepiploic artery , chymase , medicine , cardiology , artery , anatomy , bypass grafting , mast cell , immunology

Recent reports have demonstrated that long-term patency of the gastroepiploic artery (GEA) in coronary artery bypass grafting (CABG) is less satisfactory compared with the internal thoracic artery (ITA). However, the reason has not been fully elucidated. Angiotensin II is known to play an important role in the development of intimal hyperplasia, we hypothesized that the GEA is different from the ITA with respect to angiotensin II-forming ability. Accordingly, we measured activities of angiotensin II-forming enzymes, angiotensin-converting enzyme (ACE) and chymase, in human GEA and ITA.

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