Open AccessNeutrophil dysfunction after biomaterial contact in an in vitro model of cardiopulmonary bypass
Author(s) -
Anders Åsberg,
Vibeke Videm
Publication year - 2006
Publication title -
european journal of cardio-thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 133
eISSN - 1873-734X
pISSN - 1010-7940
DOI - 10.1016/j.ejcts.2006.08.019
Subject(s) - superoxide , degranulation , endothelial stem cell , chemistry , adhesion , cardiopulmonary bypass , gelatin , neutrophil extracellular traps , immunology , in vitro , medicine , biochemistry , inflammation , receptor , organic chemistry , enzyme
Cardiopulmonary bypass (CPB) induces neutrophil degranulation and superoxide anion production in vivo. We hypothesized that CPB-associated neutrophil dysregulation alters neutrophil adhesion to vascular endothelial cells and the extracellular matrix.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom