Fascin immunoreactivity for preoperatively predicting lymph node metastases in peripheral adenocarcinoma of the lung 3cm or less in diameter | Zendy

Peter Choi | Zendy; David J. Yang | Zendy; ChangGue Son | Zendy; K LEE | Zendy; JiHyun Lee | Zendy; M ROH | Zendy

Open Access

Fascin immunoreactivity for preoperatively predicting lymph node metastases in peripheral adenocarcinoma of the lung 3cm or less in diameter

Author(s) -

Peter Choi,

David J. Yang,

ChangGue Son,

K LEE,

JiHyun Lee,

M ROH

Publication year - 2006

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1016/j.ejcts.2006.06.029

Subject(s) - peripheral , fascin , medicine , adenocarcinoma , lymph node , lung , pathology , adenocarcinoma of the lung , radiology , immunohistochemistry , cancer

Fascin is an actin-bundling protein that induces cell membrane protrusions and increases the motility of normal and transformed epithelial cells. We evaluated the expression of fascin by performing immunohistochemistry to determine its role in the progression of small-size peripheral lung adenocarcinomas and to elucidate its utility as a preoperative novel therapeutic option.

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