Administration of C1-esterase inhibitor during emergency coronary artery bypass surgery in acute ST-elevation myocardial infarction☆
Author(s) -
Matthias Thielmann,
G Marggraf,
Markus Neuhäuser,
Joerg Forkel,
Ulf Herold,
Markus Kamler,
Parwis Massoudy,
Heinz Jakob
Publication year - 2006
Publication title -
european journal of cardio-thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 133
eISSN - 1873-734X
pISSN - 1010-7940
DOI - 10.1016/j.ejcts.2006.04.022
Subject(s) - medicine , myocardial infarction , troponin i , cardiology , bolus (digestion) , adverse effect , anesthesia , complement system , artery , immune system , immunology
Myocardial inflammatory response including complement activation was demonstrated as an important mechanism of ischemia-reperfusion injury and complement inhibition by C1-esterase inhibitor (C1-INH) has recently shown to have cardioprotective effects in experimental and clinical settings.
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