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Time-related risk of the St. Jude Silzone heart valve
Author(s) -
Gary L. Grunkemeier,
Rui Jin,
Canqing Yu,
Richard Holubkov,
E KENNARD,
Hartzell V. Schaff
Publication year - 2006
Publication title -
european journal of cardio-thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 133
eISSN - 1873-734X
pISSN - 1010-7940
DOI - 10.1016/j.ejcts.2006.04.012
Subject(s) - medicine , endocarditis , mechanical heart , cardiology , hazard ratio , mitral valve , leak , incidence (geometry) , aortic valve , statistical significance , implant , surgery , confidence interval , physics , optics , environmental engineering , engineering
The St. Jude Medical Silzone heart valve had a silver-impregnated sewing ring designed to reduce the incidence of prosthetic valve endocarditis. Recruitment to the randomized AVERT study comparing Silzone valves with non-Silzone Control valves was stopped because of an increased risk of reoperation for paravalvular leak, but patient follow-up continues. Determining the time-related risk profile of the Silzone valve is important for helping physicians manage the approximately 28,000 patients currently alive with a Silzone valve.

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