Changes in myocardial free amino acids during pediatric cardiac surgery: a randomised controlled trial of three cardioplegic techniques | Zendy

Paul Modi | Zendy; M.Saadeh Suleiman | Zendy; Barnaby C Reeves | Zendy; Ashwinikumar Pawade | Zendy; A PARRY | Zendy; Gianni D. Angelini | Zendy; Massimo Caputo | Zendy

Open Access

Changes in myocardial free amino acids during pediatric cardiac surgery: a randomised controlled trial of three cardioplegic techniques

Author(s) -

Paul Modi,

M.Saadeh Suleiman,

Barnaby C Reeves,

Ashwinikumar Pawade,

A PARRY,

Gianni D. Angelini,

Massimo Caputo

Publication year - 2006

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1016/j.ejcts.2006.03.035

Subject(s) - medicine , taurine , anesthesia , cardiology , ischemia , glutamine , amino acid , surgery , biochemistry , chemistry

The developing heart has a much greater dependence on amino acid (AA) metabolism than the adult heart in determining its ischemic tolerance. Blood cardioplegia preserves myocardial free AAs in adult hearts but no clinical studies have looked at the effect of different cardioplegic techniques on intracellular free AAs in the pediatric heart.

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