Comparison of the inflammatory response between miniaturized and standard CPB circuits in aortic valve surgery | Zendy

O Bical | Zendy; Yves Fromes | Zendy; Didier Gaillard | Zendy; Marc Fischer | Zendy; Olivier Ponzio | Zendy; Philippe Deleuze | Zendy; Marie-Françoise Gerhardt | Zendy; F Trivin | Zendy

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Comparison of the inflammatory response between miniaturized and standard CPB circuits in aortic valve surgery

Author(s) -

O Bical,

Yves Fromes,

Didier Gaillard,

Marc Fischer,

Olivier Ponzio,

Philippe Deleuze,

Marie-Françoise Gerhardt,

F Trivin

Publication year - 2006

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1016/j.ejcts.2006.01.053

Subject(s) - medicine , elastase , cardiopulmonary bypass , cardiac surgery , hematocrit , inflammatory response , neutrophil elastase , systemic inflammatory response syndrome , anesthesia , surgery , inflammation , sepsis , chemistry , biochemistry , enzyme

One of the complications of CPB is the systemic inflammatory response syndrome (SIRS). Recent developments tend to minimize the biological impact of CPB in using miniaturized closed circuit with reduced priming volume and less blood-air interface. The benefit of these miniaturized closed circuits in terms of inflammatory response has been proved in coronary surgery. However, in open heart surgery, the CPB circuit is no more closed and the benefit of the miniaturized set-up could disappear. The aim of the study is to compare the SIRS between standard and miniaturized circuits in aortic surgery.

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