Amniotic mesenchymal cells autotransplanted in a porcine model of cardiac ischemia do not differentiate to cardiogenic phenotypes
Author(s) -
Saverio Sartore,
Marco Lenzi,
Annalisa Angelini,
Angela Chiavegato,
Lisa Gasparotto,
Paolo De Coppi,
Roberto Bianco,
Gino Gerosa
Publication year - 2005
Publication title -
european journal of cardio-thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 133
eISSN - 1873-734X
pISSN - 1010-7940
DOI - 10.1016/j.ejcts.2005.07.019
Subject(s) - mesenchymal stem cell , transplantation , andrology , embryonic stem cell , cardiac function curve , biology , stem cell , microbiology and biotechnology , pathology , immunology , medicine , heart failure , biochemistry , gene
Transplantation of stem cells in the acute ischemic myocardium (AMI) may play a role in the recovery of cardiac function. Here, we investigated the ability of amniotic fluid-derived mesenchymal cells (AFC) for phenotypic conversion to vascular cells and cardiomyocytes (CM) when autotransplanted in a porcine model of AMI.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom