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Use of an allograft patch in repair of hypoplastic left heart syndrome may complicate future transplantation
Author(s) -
Sylvain Meyer,
Pat Campbell,
James Rutledge,
Anne Halpin,
Lois E. Hawkins,
Jeremy H. Lakey,
Ivan M. Rebeyka,
Donald Ross
Publication year - 2005
Publication title -
european journal of cardio-thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 133
eISSN - 1873-734X
pISSN - 1010-7940
DOI - 10.1016/j.ejcts.2004.12.033
Subject(s) - medicine , hypoplastic left heart syndrome , panel reactive antibody , heart transplantation , transplantation , prospective cohort study , human leukocyte antigen , surgery , antibody , great arteries , cardiology , heart disease , antigen , immunology , kidney transplantation
Cryopreserved allograft tissue used in the Norwood procedure for infants with hypoplastic left heart syndrome (HLHS) has the potential to cause marked immunologic sensitization which may complicate potential future heart transplantation, if required. The purpose of this study was to assess the anti-HLA antibody response to allograft patches used in the initial repair of HLHS.

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