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Impaired circulating dendritic cell reconstitution identifies rejecting recipients after clinical heart transplantation independent of rejection therapy☆
Author(s) -
Petros Athanassopoulos,
Leonard M.B. Vaessen,
Aggie H.M.M. Balk,
Johanna J.M. Takkenberg,
Alex P.W.M. Maat,
Willem Weimar,
Ad J.J.C. Bogers
Publication year - 2005
Publication title -
european journal of cardio-thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 133
eISSN - 1873-734X
pISSN - 1010-7940
DOI - 10.1016/j.ejcts.2004.12.032
Subject(s) - medicine , immunosuppression , incidence (geometry) , heart transplantation , transplantation , myeloid , biopsy , gastroenterology , immunology , physics , optics
Dendritic cell (DC) mediated allo-antigen presentation to host antigen specific T-lymphocytes initiates acute allograft rejection. We investigated peripheral blood DC (PBDC) incidence and DC subset reconstitution in relation to histological diagnosis of acute cellular rejection (AR) and administration of rejection therapy after clinical heart transplantation (post-HTx).

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