Upregulation of endothelial adhesion molecules in hearts with congestive and ischemic cardiomyopathy: immunohistochemical evaluation of inflammatory endothelial cell activation | Zendy

Michaela Wilhelmi | Zendy; Rainer Leyh | Zendy; A HAVERICH | Zendy

Open Access

Upregulation of endothelial adhesion molecules in hearts with congestive and ischemic cardiomyopathy: immunohistochemical evaluation of inflammatory endothelial cell activation

Author(s) -

Michaela Wilhelmi,

Rainer Leyh,

A HAVERICH

Publication year - 2004

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1016/j.ejcts.2004.09.027

Subject(s) - von willebrand factor , cell adhesion molecule , heart failure , endothelial activation , ischemic cardiomyopathy , endothelium , pathogenesis , coronary artery disease , pathology , medicine , immunology , platelet , ejection fraction

In recent years many data emphasized, that inflammatory reactions seem to be involved in the pathogenesis of ischemic (ICM) and congestive (CCM) heart disease. Since, it is well known that endothelial adhesion molecules play a pivotal role in the initiation and maintenance of inflammatory reactions we therefore, evaluated the endothelial expression of a wide variety of different adhesion molecules in hearts suffering from ICM and CCM.

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