Morphological, electrophysiological and coupling characteristics of bone marrow-derived mononuclear cells?an in vitro-model | Zendy

Ardawan Rastan | Zendy; Thomas Walther | Zendy; Martin Kostelka | Zendy; Jens Garbade | Zendy; A. Schubert | Zendy; Anita Stein | Zendy; Stefan Dhein | Zendy; F. W. Mohr | Zendy

Open Access

Morphological, electrophysiological and coupling characteristics of bone marrow-derived mononuclear cells?an in vitro-model

Author(s) -

Ardawan Rastan,

Thomas Walther,

Martin Kostelka,

Jens Garbade,

A. Schubert,

Anita Stein,

Stefan Dhein,

F. W. Mohr

Publication year - 2004

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1016/j.ejcts.2004.08.033

Subject(s) - lucifer yellow , gap junction , connexin , microinjection , patch clamp , electrophysiology , bone marrow , myocyte , coupling (piping) , microbiology and biotechnology , transplantation , heterologous , medicine , chemistry , intracellular , biology , biochemistry , materials science , gene , metallurgy

Transplantation of bone marrow-derived mononuclear cells (BMC) may be suitable to prevent myocardial remodeling and improve left ventricular function after myocardial infarction. However, it is unknown whether or not cardiomyocytes and BMCs can form functioning cell-to-cell coupling and develop adequate electrophysiological properties.

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