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A combined small cell carcinoma of the lung containing three components: small cell, spindle cell and squamous cell carcinoma
Author(s) -
Masanori Gotoh,
Yasuo Yamamoto,
ChienSheng Huang,
H. Yokomise
Publication year - 2004
Publication title -
european journal of cardio-thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 133
eISSN - 1873-734X
pISSN - 1010-7940
DOI - 10.1016/j.ejcts.2004.08.002
Subject(s) - spindle cell carcinoma , medicine , small cell carcinoma , malignancy , carcinoma , biopsy , cell , radiology , basal cell , chemotherapy , lung , squamous cell carcinoma of the lung , small cell lung carcinoma , pathology , large cell , adenocarcinoma , cancer , biology , genetics
A 61-year-old man was referred to our hospital because of rapid growth of a mass shadow revealed by chest radiography. The mass was diagnosed as pure small cell carcinoma by CT-guided needle biopsy, and the patient underwent chemotherapy. However, as the tumor showed no response, we considered the possibility of some other form of malignancy and performed surgery. Postoperatively, the mass was diagnosed as small cell carcinoma combined with small cell, spindle cell and squamous cell carcinoma. We report this case in view of the rarity of this combination of morphologic patterns in a primary bronchogenic carcinoma.

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