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Myocardial protective effect of FR167653; a novel cytokine inhibitor in ischemic-reperfused rat heart
Author(s) -
Alexey N. Aleshin
Publication year - 2004
Publication title -
european journal of cardio-thoracic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.303
H-Index - 133
eISSN - 1873-734X
pISSN - 1010-7940
DOI - 10.1016/j.ejcts.2004.06.021
Subject(s) - medicine , ischemia , cytokine , cardiology , inotrope , ischemic preconditioning , pharmacology , anesthesia
In this study, a newly synthesized cytokine inhibitor FR167653 was investigated using a rat heart ischemia-reperfusion model to prove its myocardial protective effect and its role in the inhibition of cytokine production in ischemic myocardium.

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