Structural and biomolecular changes in aorta and pulmonary trunk of patients with aortic aneurysm and valve disease: implications for the Ross procedure☆ | Zendy

FranzXaver Schmid | Zendy; Katrin Bielenberg | Zendy; Stephan Holmer | Zendy; Karla Lehle | Zendy; Behrus Djavidani | Zendy; Christopher Prasser | Zendy; Christoph Wiesenack | Zendy; Dietrich E. Birnbaum | Zendy

Open Access

Structural and biomolecular changes in aorta and pulmonary trunk of patients with aortic aneurysm and valve disease: implications for the Ross procedure☆

Author(s) -

FranzXaver Schmid,

Katrin Bielenberg,

Stephan Holmer,

Karla Lehle,

Behrus Djavidani,

Christopher Prasser,

Christoph Wiesenack,

Dietrich E. Birnbaum

Publication year - 2004

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1016/j.ejcts.2004.02.028

Subject(s) - bicuspid aortic valve , ascending aorta , medicine , aorta , aortic valve , aneurysm , aortic aneurysm , pathology , cardiology , surgery

A higher incidence of pulmonary autograft dilatation is assumed in patients with ascending aortic dilatation and bicuspid aortic valve disease. To examine whether structural abnormalities are present in the ascending aorta as well as in the pulmonary trunk (PT) we specifically addressed molecular mechanisms and signalling pathways for aneurysm formation in ascending aortic aneurysms and PT of patients with different aortic valve pathology undergoing an extended Ross procedure.

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