Diltiazem provides higher internal mammary artery flow than nitroglycerin during coronary artery bypass grafting surgery | Zendy

Yılmaz Tabel | Zendy; Hasan Hepağuşlar | Zendy; Cenk Erdal | Zendy; Hüdai Çatalyürek | Zendy; Ünal Açıkel | Zendy; Zahi̇de Elar | Zendy; Özgür Aslan | Zendy

Open Access

Diltiazem provides higher internal mammary artery flow than nitroglycerin during coronary artery bypass grafting surgery

Author(s) -

Yılmaz Tabel,

Hasan Hepağuşlar,

Cenk Erdal,

Hüdai Çatalyürek,

Ünal Açıkel,

Zahi̇de Elar,

Özgür Aslan

Publication year - 2004

Publication title -

european journal of cardio-thoracic surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.303

H-Index - 133

eISSN - 1873-734X

pISSN - 1010-7940

DOI - 10.1016/j.ejcts.2004.01.004

Subject(s) - medicine , diltiazem , vasospasm , perioperative , artery , anesthesia , derivation , hemodynamics , coronary artery bypass surgery , mammary artery , cardiology , surgery , subarachnoid hemorrhage , calcium

Perioperative internal mammary artery (IMA) vasospasm in patients undergoing coronary artery bypass grafting (CABG) surgery may lead to morbidity and mortality. Surgical stimulus is one of the common causes of IMA vasospasm. Preventive measures, beside treatment should be taken into consideration to obtain vasospasm free IMA. The effect of a pharmacologic agent on IMA flow when it is administered before harvesting the artery has not been documented. We designed a prospective randomized clinical study to compare the IMA free blood flows in patients receiving either diltiazem or nitroglycerin, starting infusion of study drugs before a surgical stimulus was applied to the IMA region and continuing throughout the isolation period.

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