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Cellular repopulation of myocardial infarction in patients with sex-mismatched heart transplantation*1
Author(s) -
E HOCHTZEISBERG
Publication year - 2004
Publication title -
european heart journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.336
H-Index - 293
eISSN - 1522-9645
pISSN - 0195-668X
DOI - 10.1016/j.ehj.2004.01.017
Subject(s) - medicine , myocardial infarction , progenitor cell , transplantation , regeneration (biology) , infarction , stem cell , cardiology , cd68 , pathology , microbiology and biotechnology , immunohistochemistry , biology
Recent studies have suggested that human extracardiac progenitor cells are capable of differentiating into cardiomyocytes. In animal studies, myocardial infarction attracted bone marrow stem cells and enhanced their differentiation into cardiomyocytes. Based on these findings, we hypothesised that myocardial infarction stimulates the invasion of progenitor cells and their differentiation into endothelial and cardiac cells in the human heart.

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