The spectrum of biochemical alterations associated with organ dysfunction and inflammatory status and their association with disease outcomes in severe COVID-19: A longitudinal cohort and time-series design study | Zendy

Abderrahim Oussalah | Zendy; Stanislas Gleye | Zendy; Isabelle Clerc Urmes | Zendy; Elodie Laugel | Zendy; Françoise Barbé | Zendy; Sophie Orlowski | Zendy; Catherine Malaplate | Zendy; Isabelle AimoneGastin | Zendy; Beatrice Maatem Caillierez | Zendy; Marc Merten | Zendy; Élise Jeannesson | Zendy; Raphaël Kormann | Zendy; Jean-Luc Olivier | Zendy; Rosa-Maria Rodríguez-Guéant | Zendy; Farès Namour | Zendy; Sybille Bevilacqua | Zendy; Nathalie Thilly | Zendy; Marie-Reine Losser | Zendy; Antoine Kimmoun | Zendy; Luc Frimat | Zendy; Bruno Lévy | Zendy; Sébastien Gibot | Zendy; Évelyne Schvoerer | Zendy; JeanLouis Guéant | Zendy

Open Access

The spectrum of biochemical alterations associated with organ dysfunction and inflammatory status and their association with disease outcomes in severe COVID-19: A longitudinal cohort and time-series design study

Author(s) -

Abderrahim Oussalah,

Stanislas Gleye,

Isabelle Clerc Urmes,

Elodie Laugel,

Françoise Barbé,

Sophie Orlowski,

Catherine Malaplate,

Isabelle AimoneGastin,

Beatrice Maatem Caillierez,

Marc Merten,

Élise Jeannesson,

Raphaël Kormann,

Jean-Luc Olivier,

Rosa-Maria Rodríguez-Guéant,

Farès Namour,

Sybille Bevilacqua,

Nathalie Thilly,

Marie-Reine Losser,

Antoine Kimmoun,

Luc Frimat,

Bruno Lévy,

Sébastien Gibot,

Évelyne Schvoerer,

JeanLouis Guéant

Publication year - 2020

Publication title -

eclinicalmedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.915

H-Index - 20

ISSN - 2589-5370

DOI - 10.1016/j.eclinm.2020.100554

Subject(s) - medicine , retrospective cohort study , odds ratio , cohort study , organ dysfunction , cohort , systemic inflammatory response syndrome , gastroenterology , sepsis

Our results point out the lack of the association between the inflammatory markers and the risk of death but rather highlight a significant association between renal dysfunction and the risk of COVID-19 related acute respiratory failure and death.

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