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Endpoints used in phase III randomized controlled trials of treatment options for COVID-19
Author(s) -
Aakash Desai,
Bishal Gyawali
Publication year - 2020
Publication title -
eclinicalmedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.915
H-Index - 20
ISSN - 2589-5370
DOI - 10.1016/j.eclinm.2020.100403
Subject(s) - medicine , randomized controlled trial , clinical endpoint , surrogate endpoint , clinical trial , intensive care medicine
Ordinal Scale endpoints 21 (43%) Survival without needs of ventilator utilization 4 (8%) Overall or All-Cause Mortality 3 (6%) Viral Clearance 3 (6%) Clinical stability/remission endpoints 2 (4%) Lung injury score 2 (4%) No. of deaths/need for intubation 2 (4%) Clear Chest CT/Negative PCR 2 (4%) Change in PaO2/FiO2 1 (2%) Rate of comprehensive adverse outcome 1 (2%) % ICU transfers 1 (2%) % Return to Room Air 1 (2%) Hours to recovery 1 (2%) Number of deceased participants or with persistent organ dysfunction 1 (2%)

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