Genetic risk for dengue hemorrhagic fever and dengue fever in multiple ancestries
Author(s) -
Guillaume Paré,
Binod Neupane,
Sasha Eskandarian,
Eva Harris,
Scott B. Halstead,
Lionel Gresh,
Guillermina Kuan,
Ángel Balmaseda,
Luis Villar,
Elsa Rojas,
Jorge E. Osorio,
Đặng Đức Anh,
Aruna Dharshan De Silva,
Sunil Premawansa,
Gayani Premawansa,
Ananda Wijewickrama,
Ivette Lorenzana,
Leda Parham,
Cynthia Rodríguez,
Ildefonso FernándezSalas,
Rosa SánchezCasas,
Esteban E. DíazGonzález,
Khin Saw Aye,
Win Lai May,
M Thein,
Filemón Bucardo,
Yaoska Reyes,
Patricia Blandón,
Kenji Hirayama,
Lan Weiss,
Pardeep Singh,
Jennifer Newton,
Mark Loeb
Publication year - 2020
Publication title -
ebiomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.596
H-Index - 63
ISSN - 2352-3964
DOI - 10.1016/j.ebiom.2019.11.045
Subject(s) - dengue fever , odds ratio , single nucleotide polymorphism , quartile , genome wide association study , medicine , demography , immunology , genetics , biology , genotype , gene , confidence interval , sociology
There is a strong genetic effect that predisposes to risk of DHF/DSS and DF. The genetic risk for DHF/DSS is higher than that for DF when compared to controls, and this effect persists across multiple ancestries.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom