Identification of novel genome-wide associations for suicidality in UK Biobank, genetic correlation with psychiatric disorders and polygenic association with completed suicide | Zendy

Rona J. Strawbridge | Zendy; Joey Ward | Zendy; Amy Ferguson | Zendy; Nicholas Graham | Zendy; Richard Shaw | Zendy; Breda Cullen | Zendy; Robert Pearsall | Zendy; Laura M. Lyall | Zendy; Keira J.A. Johnston | Zendy; Claire L. Niedzwiedz | Zendy; Jill P. Pell | Zendy; Daniel Mackay | Zendy; Julie Langan Martin | Zendy; Donald M. Lyall | Zendy; Mark E.S. Bailey | Zendy; Daniel J. Smıth | Zendy

Open Access

Identification of novel genome-wide associations for suicidality in UK Biobank, genetic correlation with psychiatric disorders and polygenic association with completed suicide

Author(s) -

Rona J. Strawbridge,

Joey Ward,

Amy Ferguson,

Nicholas Graham,

Richard Shaw,

Breda Cullen,

Robert Pearsall,

Laura M. Lyall,

Keira J.A. Johnston,

Claire L. Niedzwiedz,

Jill P. Pell,

Daniel Mackay,

Julie Langan Martin,

Donald M. Lyall,

Mark E.S. Bailey,

Daniel J. Smıth

Publication year - 2019

Publication title -

ebiomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.596

H-Index - 63

ISSN - 2352-3964

DOI - 10.1016/j.ebiom.2019.02.005

Subject(s) - biobank , psychiatry , population , medicine , genome wide association study , suicide attempt , mental health , poison control , bipolar disorder , suicide prevention , psychology , genetics , medical emergency , single nucleotide polymorphism , biology , environmental health , mood , gene , genotype

Suicide is a major issue for global public health. Suicidality describes a broad spectrum of thoughts and behaviours, some of which are common in the general population. Although suicide results from a complex interaction of multiple social and psychological factors, predisposition to suicidality is at least partly genetic.

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