The Gametocytocidal Efficacy of Different Single Doses of Primaquine with Dihydroartemisinin-piperaquine in Asymptomatic Parasite Carriers in The Gambia: A Randomized Controlled Trial | Zendy

Joseph Okebe | Zendy; Teun Bousema | Zendy; Muna Affara | Zendy; Gian Luca Di Tanna | Zendy; Edgard Dabira | Zendy; Abdoulaye Gaye | Zendy; Frank Sanya-Isijola | Zendy; Henry Badji | Zendy; Simon Correa | Zendy; Davis Nwakanma | Zendy; JeanPierre Van Geertruyden | Zendy; Chris Drakeley | Zendy; Umberto D’Alessandro | Zendy

Open Access

The Gametocytocidal Efficacy of Different Single Doses of Primaquine with Dihydroartemisinin-piperaquine in Asymptomatic Parasite Carriers in The Gambia: A Randomized Controlled Trial

Author(s) -

Joseph Okebe,

Teun Bousema,

Muna Affara,

Gian Luca Di Tanna,

Edgard Dabira,

Abdoulaye Gaye,

Frank Sanya-Isijola,

Henry Badji,

Simon Correa,

Davis Nwakanma,

JeanPierre Van Geertruyden,

Chris Drakeley,

Umberto D’Alessandro

Publication year - 2016

Publication title -

ebiomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.596

H-Index - 63

ISSN - 2352-3964

DOI - 10.1016/j.ebiom.2016.10.032

Subject(s) - primaquine , medicine , gametocyte , dihydroartemisinin , malaria , artesunate , plasmodium falciparum , asymptomatic , clinical endpoint , artemisinin , stavudine , gastroenterology , pharmacology , randomized controlled trial , virology , immunology , chloroquine , viral load , human immunodeficiency virus (hiv) , antiretroviral therapy

Asymptomatic low-density gametocyte carriers represent the majority of malaria-infected individuals. However, the impact of recommended treatment with single low dose of primaquine and an artemisinin-based combination therapy to reduce transmission in this group is unknown.

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