Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study | Zendy

Helen RossAdams | Zendy; Alastair Lamb | Zendy; Mark Dunning | Zendy; Silvia Halim | Zendy; Johan Lindberg | Zendy; Charles Massie | Zendy; Lars Egevad | Zendy; Robert B. Russell | Zendy; Antonio RamosMontoya | Zendy; Sarah L. Vowler | Zendy; Nitin Sharma | Zendy; Jonathan Kay | Zendy; Hayley C. Whitaker | Zendy; J Clark | Zendy; Rachel Hurst | Zendy; Vincent J. Gnanapragasam | Zendy; Nimish Shah | Zendy; Anne Y. Warren | Zendy; Christopher S. Cooper | Zendy; Andy G. Lynch | Zendy; Rory Stark | Zendy; Ian G. Mills | Zendy; Henrik Grönberg | Zendy; David E. Neal | Zendy

Open Access

Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study

Author(s) -

Helen RossAdams,

Alastair Lamb,

Mark Dunning,

Silvia Halim,

Johan Lindberg,

Charles Massie,

Lars Egevad,

Robert B. Russell,

Antonio RamosMontoya,

Sarah L. Vowler,

Nitin Sharma,

Jonathan Kay,

Hayley C. Whitaker,

J Clark,

Rachel Hurst,

Vincent J. Gnanapragasam,

Nimish Shah,

Anne Y. Warren,

Christopher S. Cooper,

Andy G. Lynch,

Rory Stark,

Ian G. Mills,

Henrik Grönberg,

David E. Neal

Publication year - 2015

Publication title -

ebiomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.596

H-Index - 63

ISSN - 2352-3964

DOI - 10.1016/j.ebiom.2015.07.017

Subject(s) - risk stratification , prostate cancer , transcriptome , computational biology , oncology , cohort , medicine , stratification (seeds) , bioinformatics , biology , cancer , genetics , gene , gene expression , seed dormancy , germination , botany , dormancy

Understanding the heterogeneous genotypes and phenotypes of prostate cancer is fundamental to improving the way we treat this disease. As yet, there are no validated descriptions of prostate cancer subgroups derived from integrated genomics linked with clinical outcome.

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