Telomere G-tail Length is a Promising Biomarker Related to White Matter Lesions and Endothelial Dysfunction in Patients With Cardiovascular Risk: A Cross-sectional Study | Zendy

Tomohisa Nezu | Zendy; Naohisa Hosomi | Zendy; Tetsuya Takahashi | Zendy; Kumiko Anno | Zendy; Shiro Aoki | Zendy; Akira Shimamoto | Zendy; Hirofumi Maruyama | Zendy; Tomonori Hayashi | Zendy; Masayasu Matsumoto | Zendy; Hidetoshi Tahara | Zendy

Open Access

Telomere G-tail Length is a Promising Biomarker Related to White Matter Lesions and Endothelial Dysfunction in Patients With Cardiovascular Risk: A Cross-sectional Study

Author(s) -

Tomohisa Nezu,

Naohisa Hosomi,

Tetsuya Takahashi,

Kumiko Anno,

Shiro Aoki,

Akira Shimamoto,

Hirofumi Maruyama,

Tomonori Hayashi,

Masayasu Matsumoto,

Hidetoshi Tahara

Publication year - 2015

Publication title -

ebiomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.596

H-Index - 63

ISSN - 2352-3964

DOI - 10.1016/j.ebiom.2015.05.025

Subject(s) - telomere , cross sectional study , biomarker , medicine , endothelial dysfunction , pathology , bioinformatics , biology , genetics , dna

The telomeric 3'-overhang (G-tail) length is essential for the biological effects of telomere dysfunction in vitro, but the association of length with aging and cardiovascular risk is unclear in humans. We investigated the association between the telomere G-tail length of leukocytes and cardiovascular risk, age-related white matter changes (ARWMCs), and endothelial function.

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